SUPRAMOLECULAR SELF-ASSEMBLY

         Inspired by the fascinating possibilities for novel properties in non-covalently linked molecules, the Gibson group began work in this area in 1986.  Most of our effort has focused on applications in the polymer field, but in order to achieve our goals we have done and continue to do a lot of classical organic synthesis in order to improve the basic building blocks; in this regard X-ray crystallography has been a powerful tool. In the past we have prepared small molecule pseudorotaxanes, polypseudorotaxanes and polyrotaxanes of various types as the cartoons below illustrate.  The formation of the pseudorotaxane efficiently from the cyclic host and linear guest components is a necessary pre-requisite for achieving our current goals, which are the selective and efficient self-assembly of supramolecular polymers and non-covalent block and star polymers.